Albert Einstein College of Medicine, Anatomy & Structural Biology

Blossom Damania, Ph.D. Jack Griffith, Ph.D.

Dr. Costantini is currently Assistant Professor in the Biological and Biomedical Sciences program at North Carolina Central University in Durham, NC

Fall 2016

• Introduction to Human Viruses and Viral Pathogenesis, North Carolina Central University

Spring 2016

• Molecular Biology of Cells, North Carolina Central University

McNamara RP- Eason AB- Zhou Y- Bigi R- Griffith JD- Costantini LM- Rudek MA- Anders NM- Damania BA- Dittmer DP. Exosome-Encased Nucleic Acid Scaffold Chemotherapeutic Agents for Superior Anti-Tumor and Anti-Angiogenesis Activity. ACS bio & med chem Au. 2022 Apr 20;2(2):140-149. PMCID: PMC9026271. 

McNamara RP, Zhou Y, Eason AB, Landis JT, Chambers MG, Willcox S, Peterson TA, Schouest B, Maness NJ, MacLean AG, Costantini LM, Griffith JD, Dittmer DP. Imaging of surface microdomains on individual extracellular vesicles in 3-D. J Extracell Vesicles. 2022 Mar;11(3):e12191. doi: 10.1002/jev2.12191. PMID: 35234354; PMCID: PMC8888793.

Krokhotin A, Sarker M, Sevilla EA, Costantini LM, Griffith JD, Campbell SL, Dokholyan NV. Distinct Binding Modes of Vinculin Isoforms Underlie Their Functional Differences Structure. 2019 Oct 1;27(10):1527-1536. PMCID: PMC6774862 McNamara RP, Chugh PE, Bailey A, Costantini LM, Ma Z, Bigi R, Cheves A, Eason AB, Landis JT, Host KM, Xiong J, Griffith JD, Damania B, Dittmer DP. Extracellular vesicles from Kaposi Sarcoma-associated herpesvirus lymphoma induce long-term endothelial cell reprogramming.  PLoS Pathog. 2019 Feb 4;15(2):e1007536. PMCID: PMC6361468. Sarker M, Lee HT, Mei L, Krokhotin A, de Los Reyes SE, Yen L, Costantini LM, Griffith J, Dokholyan NV, Alushin GM, Campbell SL. Cardiomyopathy Mutations in Metavinculin Disrupt Regulation of Vinculin-Induced F-Actin Assemblies.  J Mol Biol. 2019 Apr 5;431(8):1604-1618. PMCID: PMC6693633 McNamara RP, Caro-Vegas CP, Costantini LM, Landis JT, Griffith JD, Damania BA, Dittmer DP. Large-scale, cross-flow based isolation of highly pure and endocytosis-competent extracellular vesicles.  J Extracell Vesicles. 2018 Nov 30;7(1):1541396  PMCID: PMC6282418 McNamara RP, Costantini LM, Myers TA, Schouest B, Maness NJ, Griffith JD, Damania BA, MacLean AG, Dittmer DP. Nef Secretion into Extracellular Vesicles or Exosomes Is Conserved across Human and Simian Immunodeficiency Viruses.. mBio. 2018 Feb 6;9(1). 10.1128/mBio.02344-17. 29437924. PMCID: PMC5801467 Host KM- Jacobs SR- West JA- Zhang Z- Costantini LM– Stopford CM- Dittmer DP- Damania B. 2017. Kaposi’s Sarcoma-Associated Herpesvirus Increases PD-L1 and Proinflammatory Cytokine Expression in Human Monocytes.. mBio. Oct 10;8(5). ·  PMCID: PMC5635685