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Chris Arena, Ph.D.

Biomedical Engineering


Virginia Tech – Biomedical Engineering


Paul Dayton, Ph.D.


Dr. Arena is Collegiate Associate Professor in the Department of Biomedical Engineering and Mechanics at Virginia Tech, in Blacksburg, VA.


Spring 2015

  • Biomedical Imaging and Devices, Department of Chemical, Biological, and BioEngineering, North Carolina A&T State University.


Wu SY, Fix SM, Arena CB, Chen CC, Zheng W, Olumolade OO, Papadopoulou V, Novell A, Dayton PA, Konofagou EE. 2018. Focused ultrasound-facilitated brain drug delivery using optimized nanodroplets: vaporization efficiency dictates large molecular delivery Phys Med Biol. 2018 Jan 22;63(3). PMCID: PMC5823501

Fix SM- Novell A- Yun Y- Dayton PA- Arena CB. An evaluation of the sonoporation potential of low-boiling point phase-change ultrasound contrast agents in vitro.. Journal of therapeutic ultrasound. 2017;5:7 PMCID: PMC5260003

Novell A, Arena CB, Oralkan O, & Dayton PA. 2016. Wideband acoustic activation and detection of droplet vaporization events using a capacitive micromachined ultrasonic transducer. Journal of the Acoustical Society of America. 60(8): 3111. PMCID: PMC5848826

Porter TR- Arena CB- Sayyed S- Lof J- High RR- Xie F- Dayton PA. 2016. Targeted Transthoracic Acoustic Activation of Systemically Administered Nanodroplets to Detect Myocardial Perfusion Abnormalities. Circulation. Cardiovascular imaging. 9(1). PMCID: PMC4697280.

Arena, CB, Novell A, Sheeran PS, Puett, C, Moyer LC, and Dayton PA. 2015. Dual-frequency acoustic droplet vaporization detection for medical imaging. IEEE Trans Ultrason Ferroelectr Freg Control. 62(9): 1623-33. PMID: 26415125. PMCID: PMC5507352

Novell A- Arena CB– Kasoji S- Dayton PA. 2015. Optimization of multi-pulse sequences for nonlinear contrast agent imaging using a cMUT array. Physics in medicine and biology.60(8):3111-27. PMCID: PMC4703325.


Sheeran PS- Rojas JD- Puett C- Hjelmquist J- Arena CB– Dayton PA. 2015. Contrast-enhanced ultrasound imaging and in vivo circulatory kinetics with low-boiling-point nanoscale phase-change perfluorocarbon agents.Ultrasound in medicine & biology. 41(3):814-31. PMCID: PMC5599113